2017

JOURNAL PUBLICATIONS

- Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model. J. Ramírez, M. Orini, A. Mincholé, V. Monasterio, I. Cygankiewicz, A. Bayés de Luna, J.P. Martínez, P. Laguna, E. Pueyo. PLOS ONE, vol 12, pp. e0186152, 2017.

- Variability of Ventricular Repolarization Dispersion Quantified by Time-Warping the Morphology of the T-waves. J. Ramírez, M. Orini, D. Tucker, E. Pueyo, P. Laguna. IEEE Trans Biomed Eng, vol. 64, pp. 1619–1630, 2017.

- Pulse rate and transit time analysis to predict hypotension events after spinal anesthesia during programmed cesarean labor. J. Bolea, J. Lázaro, E. Gil, E. Rovira, J. M. Remartínez, P. Laguna, E. Pueyo, A. Navarro, R. Bailón. Ann Biomed Eng, DOI: 10.1007/s10439-017-1864-y, 2017.

- T-wave Morphology Restitution Predicts Sudden Cardiac Death in Patients with Chronic Heart Failure. J. Ramírez, M. Orini, A. Mincholé, V. Monasterio, I. Cygankiewicz, A. Bayés de Luna, J.P. Martínez, E. Pueyo, P. Laguna. J Am Heart Assoc, vol. 6, pii. e005310, 2017.

- Atrial Fibrillation Dynamics and Ionic Block Effects in Six Heterogeneous Human 3D Virtual Atria with Distinct Repolarization Dynamics. C. Sánchez, A. Bueno-Orovio, E. Pueyo, B. Rodríguez. Front Bioeng Biotechnol, vol. 5, pp. 29, 2017.

- A Time-Varying Non-Parametric Methodology for Assessing Changes in QT Variability Unrelated to Heart Rate Variability. M. Orini, E. Pueyo, P. Laguna, R. Bailón. IEEE Trans Biomed Eng, In press, 2017.

- A methodology to improve human ventricular models for the investigation of cardiac arrhythmias. J. Carro, J. F. Rodríguez, E. Pueyo. Biophys J, vol. 112, pp. 403a, 2017. Published in abstract form.

CONFERENCE PROCEEDINGS

- Identification of parameters describing phenomenological cardiac action potential models using sigma point methods. J. Fernandez-Bes, D.A. Sampedro-Puente, E. Pueyo. Proc. XLIV International Conference on Computing in Cardiology, In press, 2017.

- Differential responses to beta-adrenergic stimulation in the long QT syndrome type 1: characterization and mechanisms. D.A. Sampedro-Puente, J. Fernandez-Bes, E. Pueyo. Proc. XLIV International Conference on Computing in Cardiology, In press, 2017.

- Quantification of T-wave Morphological Variability Using Time-warping Methods. J. Ramírez, M. Orini, E. Pueyo, P. Laguna. Proc. EMBEC 2017, pp. 478-481, 2017.

- Multiscale methods for definition of ionic variables in electrophysiological models. J. Carro, J.F. Rodríguez, E. Pueyo. Proc. EMBEC 2017, pp. 115-118, 2017.

2016

JOURNAL PUBLICATIONS

- Interactive effect of beta-adrenergic stimulation and mechanical stretch on low-frequency oscillations of ventricular action potential duration in humans. E. Pueyo, M. Orini, J. F. Rodríguez, P. Taggart. J Mol Cell Cardiol, vol. 97, pp. 93-105, 2016.

- Ischemia detection from morphological QRS angle changes. D. Romero, J. P. Martínez, P. Laguna, E. Pueyo. Physiol Meas, vol. 37, pp. 1004, 2016.

- Experimentally-based computational investigation into beat-to-beat variability in ventricular repolarization and its response to ionic current inhibition. E. Pueyo, C. E. Dangerfield, O. J. Britton, L. Virág, K. Kistamás, N. Szentandrássy, N. Jost, A. Varró, P. P. Nánási, K. Burrage, B. Rodríguez. PLoS ONE, vol. 11, pp. e0151461, 2016.

- Influence of heart rate in nonlinear HRV indices as a sampling rate effect evaluated on supine and standing. J. Bolea, E. Pueyo, M. Orini, R. Bailón. Front Physiol, vol. 7, pp. 501, 2016.

- Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols. J. Carro, J. F. Rodríguez, V. Monasterio, E. Pueyo. Prog Biophys Mol Biol, DOI: 10.1016/j.pbiomolbio.2016.11.006, 2016.

- Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block. J. Vicente, L. Johannesen, M. Hosseini, J. W. Mason, P. T. Sager, E. Pueyo, D. G. Strauss. PLoS ONE, vol. 11, pp. e0163619 , 2016.

- Techniques for ventricular repolarization instability assessment from the ECG. P. Laguna, J. P. Martínez, E. Pueyo. Proc IEEE, vol. 104, pp. 392-415, 2016.

CONFERENCE PROCEEDINGS

- An Index for T-wave Pointwise Amplitude Variability Quantification. J. Ramírez, M. Orini, J.D. Tucker, E. Pueyo, P. Laguna. Proc. XLIII International Conference on Computing in Cardiology, pp. 49-52, 2016.

2015

JOURNAL PUBLICATIONS

- High protein intake supplementation to compensate changes in ventricular repolarization due to 21-days of bedridden immobilization. EG. Caiani, A. Martín-Yebra, J. Bolea, A. Auricchio, E. Pueyo, P. Vaida. Eur Heart J, vol. 36, pp. 1145-1145, 2015.

- Erratum: QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death. J. Ramirez, P.Laguna, A. Bayés de Luna, M. Malik, E. Pueyo. J Electrocardiol, vol. 48(1), pp. 128-129, 2015.

- Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers. J. Ramírez, V. Monasterio, A. Mincholé, M. Llamedo, G. Lenis, I. Cygankiewicz, A. Bayés de Luna, M. Malik, J.P. Martínez, P. Laguna, E. Pueyo. J Electrocardiol, vol. 48, pp. 551-557, 2015.

- Comprehensive T Wave morphology assessment in a randomized clinical study of dofetilide, quinidine, ranolazine and verapamil. J. Vicente, L. Johannesen, J.W. Mason, W.J. Crumb, E. Pueyo, N. Stockbridge, D.G. Strauss. J Am Heart Assoc, vol. 4, pp. e001615, 2015.

- ECG-based estimation of dispersion of APD restitution as a tool to stratify sotalol-induced arrhythmic risk. A. Mincholé, A. Bueno-Orovio, P. Laguna, E. Pueyo, and B. Rodríguez. J Electrocardiol, vol. 48, pp. 867-873, 2015.

- Sex Differences in Drug-Induced Changes in Ventricular Repolarization. J. Vicente, L. Johannesen, J. W. Mason, E. Pueyo, N. Stockbridge, D. G. Strauss. J Electrocardiol, vol. 58(6), pp.1081-1087, 2015.

CONFERENCE PROCEEDINGS

- The role of purkinje automaticity as an arrhythmia mechanism in hyperkalaemia. V. Monasterio, J. Carro, E. Pueyo, J.F. Rodríguez. Proc. XLII International Conference on Computing in Cardiology, pp. 873-876, 2015.

2014

JOURNAL PUBLICATIONS

- An electrocardiographic biomarker of ischemic preconditioning. L.P.B. Meijs, L. Galeotti, E. Pueyo, D. Romero, R.B. Jennings, M. Ringborn, S.G. Warren, G.S. Wagner, D.G. Strauss. Am J Physiol, vol. 307, pp. 80-87, 2014.

- Na/K pump regulation of cardiac repolarization: insights from a systems biology approach. A. Bueno-Orovio, C. Sánchez, E. Pueyo, B. Rodríguez. Pflugers Arch-Eur J Physiol, vol. 466, pp. 183–19, 2014.

- Modeling and quantification of repolarization feature dependency on heart rate. A. Mincholé, E. Zacur, E. Pueyo, P. Laguna. Methods Inf Med, vol. 53, pp. 324-328, 2014.

- Electrocardiogram derived respiratory rate from QRS slopes and R-wave angle. J. Lázaro, A. Alcaine, D. Romero, E. Gil, P. Laguna, E. Pueyo, R. Bailón. Ann Biomed Eng, vol. 40, pp. 2072-2083, 2014.

- Inter-subject variability in human atrial action potential in sinus rhythm versus chronic atrial fibrillation. C. Sánchez, A. Bueno-Orovio, E. Wettwer, S. Loose, U. Ravens, E. Pueyo, B. Rodríguez. PLOS ONE, vol 9, pp. e105897, 2014.

- QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: relation to sudden cardiac death. J. Ramírez, P. Laguna, A. Bayés de Luna, M. Malik, E. Pueyo. J Electrocardiol, vol. 47, pp. 842-848, 2014.

- T wave Morphology Assessment in a Randomized Double-blind Crossover Study of Four hERG Potassium Channel Blocking Drugs. J. Vicente, L. Johannesen, R.F. Afoakwa, E. Pueyo, N. Stockbridge, J. W. Mason, D. G. Strauss. Circulation, vol.130, pp. A14051, 2014. Published in abstract form.

CONFERENCE PROCEEDINGS

- Assessing Instantaneous QT Variability dynamics within a Point-Process Nonlinear Framework. G. Valenza, M. Orin. L. Citi, A. Minchole, E. Pueyo, P. Laguna, R. Barbieri. Proc. 8th Conference Of The European Study Group On Cardiovascular Oscillations, pp. 67-68, 2014.

- Non-linear HRV indices under autonomic nervous system blockade. J. Bolea, E. Pueyo, P. Laguna and R. Bailón. Proc. 36nd Annual International Conference of the IEEE EMBS, pp. 3252-3255, 2014.

- Assessing Real-Time RR-QT Frequency-Domain Measures of Coupling and Causality through Inhomogeneous Point-Process Bivariate Models. G. Valenza, M. Orin. L. Citi, A. Minchole, E. Pueyo, P. Laguna, R. Barbieri. Proc. 36nd Annual International Conference of the IEEE EMBS, pp. 6475-6478, 2014.

- In Silico Simulations of Experimental Protocols for Cardiac Modeling. J. Carro, J. F. Rodríguez, E. Pueyo. Proc. 36nd Annual International Conference of the IEEE EMBS, pp. 5695-5698, 2014.

- Analysis of QRS Alterations during Stress Test Recordings on Patients with Brugada Syndrome. D. Romero, N. Behar, A. Martín-Yebra, J. P. Martínez, P. Laguna, E. Pueyo, G. Carrault, P. Mabo, A. Hernández. Proc. XLI International Conference on Computing in Cardiology, pp. 137-140, 2014.

- Circadian Pattern and Sex Differences of QT/RR and T-peak-to-end/RR Curvatures and Slopes in Chronic Heart Failure Patients. J. Ramírez, I. Cygankiewicz, P. Laguna, M. Malik, E. Pueyo. Proc. XLI International Conference on Computing in Cardiology, pp. 173-176, 2014.

- Detection of Acute Ischemia Episodes from QRS Angles Changes using a Laplacian Noise Model. D. Romero, J. P. Martínez, P. Laguna, E. Pueyo. Proc. XLI International Conference on Computing in Cardiology, pp. 629-632, 2014.

- Repolarization alternans in human ventricular hyperkalaemic tissue: dependence on current stimulation. V. Monasterio, J. Carro, E. Pueyo. Proc. XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp.1-4, 2014.

- Modulación Circadiana y de Género de las Relaciones QT/RR y T-pico-a-fin/RR en Pacientes con Insuficiencia Cardiaca. J. Ramírez, P. Laguna, E. Pueyo. Proc. XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp.1-4, 2014.

2013

JOURNAL PUBLICATIONS

- Signal processing guided by physiology: making the most of biomedical signals. E. Pueyo, R. Bailón, E. Gil, J.P. Martínez, P. Laguna. IEEE Signal Proc Mag, vol. 30, pp. 136–142, 2013.

- Detecting acute myocardial ischemia by evaluation of QRS angles. D. Romero, P. Laguna, E. Pueyo. Int J Bioelectromagn, vol. 15, pp. 77–82, 2013.

- Detection and quantification of acute myocardial ischemia by morphologic evaluation of QRS changes by an angle-based method. D. Romero, M. Ringborn, P. Laguna, E. Pueyo. J Electrocardiol, vol. 46, pp. 204–214, 2013.

- Coronary Artery Disease diagnosis by analysis of ECG depolarization. E. Pueyo. J Electrocardiol, vol. 46, pp. 27–28, 2013.

CONFERENCE PROCEEDINGS

- Very low frequency modulation in QRS slopes and its relation with respiration and heart rate variability during hemodialysis. D. Hernando, A. Alcaine, P. Laguna, E. Pueyo, R. Bailón. Proc. 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 5365–5368, 2013.

- Cell Repolarization Variability Modulates Atrial FibrillationDynamics in 3D Virtual Human Atria. C. Sanchez, A. Bueno-Orovio, E. Pueyo, B. Rodríguez. Proc. XL International Conference on Computing in Cardiology, pp. 911-914, 2013.

- Repolarization Variability Mechanisms and its Relation with Cardiac Arrhytmogenesis. J. F. Rodríguez, R. Sassi, E. Pueyo, L. Mainardi. Proc. XL International Conference on Computing in Cardiology, pp. 341-344, 2013.

- Morphologic Features of the ECG for Detection of Stress-Induced Ischemia. M. Llamedo, J. P. Martínez, M. Albertal, D. Romero, E. Pueyo, P. Laguna. Proc. XL International Conference on Computing in Cardiology, pp. 591-594, 2013.

- Influence of Respiration in the Very Low Frequency Modulation of QRS slopes and Heart Rate Variability in Cardiomyopathy Patients. D. Hernando, A. Alcaine, E. Pueyo, P. Laguna, M. Orini, A. Arcentales, B. Giraldo, A. Voss, A. Bayés-Genís, R. Bailón. Proc. XL International Conference on Computing in Cardiology, pp. 117-120, 2013.

- Prediction of Sudden Cardiac Death in Chronic Heart Failure Patients by Analysis of Restitution Dispersion. J. Ramírez, A. Mincholé, J. Bolea, P. Laguna, E. Pueyo. Proc. XL International Conference on Computing in Cardiology, pp. 1-4, 2013.

2012

JOURNAL PUBLICATIONS

- Characterization of ventricular depolarization changes in a porcine model of myocardial infarction. D. Romero, M. Ringborn, M. Demidova, S. Koul, P. Laguna, P. Platonov, E. Pueyo. Physiol Meas, vol. 33, pp. 1975–1991, 2012.

- The Na+/ K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue. C. Sánchez, A. Corrias, M. Davies, J. Swinton, I. Jacobson, P. Laguna, E. Pueyo, B. Rodríguez. Am J Physiol, vol. 302, pp. 1146–1159, 2012.

- Impact of Multiple Ionic Changes in Arrhythmic Risk Biomarkers in Human Ventricular Electrophysiology. J.F. Rodríguez, J. Carro, E. Pueyo, K. Burrage, B. Rodríguez. Biophys J, vol. 102(3), pp. 543– 543, 2012. Published in abstract form.

CONFERENCE PROCEEDINGS

- Ionic modulation of atrial fibrillation dynamics in a human 3D atrial model. C. Sánchez, M. Krueger, G. Seeman, O. Dössel, E. Pueyo, B. Rodríguez. Proc. Computing in Cardiology, vol. 38, pp. 137– 140, 2012.

- Characterization of cardiac repolarization response to heart rate changes provoked by a tilt test. J. Ramírez, A. Mincholé, P. Laguna, E. Pueyo. Proc. Computing in Cardiology, vol. 38, pp. 673–676, 2012.

- Microgravity effects on ventricular response to heart rate changes. J. Bolea, E.G. Caiani, E. Pueyo, P. Laguna, R. Almeida. Proc. 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS 12), Proc. 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS 12), 2012.

- A novel ECG-based biomarker quantifying APD restitution dispersion improves risk stratification following sotalol administration. A. Mincholé, A. Bueno-Orovio, P. Laguna, E. Pueyo, B. Rodríguez. Proc. VII International Workshop on Biosignal Interpretation, pp. 105–108, 2012.

- Robust characterization of repolarization adaptation to heart rate changes. A. Mincholé, E. Zacur, E. Pueyo, P. Laguna. Proc. VII International Workshop on Biosignal Interpretation, pp. 287–290, 2012.

- Detecting acute myocardial ischemia by evaluation of QRS angles. D. Romero, P. Laguna, E. Pueyo. Proc. VII International Workshop on Biosignal Interpretation, pp. 65–68, 2012.

2011

JOURNAL PUBLICATIONS

- A multi-scale investigation of repolarization variability and its role in cardiac arrhythmogenesis. E. Pueyo, A. Corrias, L. Virág, N. Jost, T. Szel, A. Varró, N. Szentandrássy, P. Nánási, K. Burrage, B. Rodríguez. Biophys J, vol. 101, pp. 2892–2902, 2011.

- A human ventricular cell model for investigation of cardiac arrhythmias under hyperkalemic conditions. J. Carro, J.F. Rodríguez, P. Laguna, E. Pueyo. Philos Trans R Soc Lond A, vol. 369, pp. 4205– 4232, 2011.

- Evaluation of depolarization changes during acute myocardial ischemia by analysis of QRS slopes. M. Ringborn, D. Romero, E. Pueyo, O. Pahlm, G. Wagner, P. Laguna, P. Platonov. J Electrocardiol, vol. 44, pp. 416–424, 2011.

- Quantification of restitution dispersion from the dynamic changes of the T wave peak to end, measured at the surface ECG. A. Mincholé, E. Pueyo, J.F. Rodríguez, E. Zacur, P. Laguna. IEEE Trans Biomed Eng, vol. 58, pp. 1172–1182, 2011.

- Depolarization changes during acute myocardial ischemia by evaluation of QRS slopes. Standard lead and vectorial approach. D. Romero, M. Ringborn, P. Laguna, O. Pahlm, E. Pueyo. IEEE Trans Biomed Eng, vol. 58, pp. 110–120, 2011.

CONFERENCE PROCEEDINGS

- Influence of simulated microgravity by head-down-bed-resting on QT/RR dynamics. J. Bolea, E. Pueyo, R. Almeida, M. Llamedo, M. Sotaquirá, J.P. Martínez, P. Laguna, E.G. Caiani. Proc. Computing in Cardiology, vol. 37, pp. 441–444, 2011.

- ECG amplitude modulation in the very-lowfrequency band in patients with angina pectoris. A. Alcaine, R. Bailón, D. Romero, E. Pueyo, P. Laguna. Proc. Computing in Cardiology, vol. 37, pp. 757– 760, 2011.

2010

JOURNAL PUBLICATIONS

- High-throughput cardiac science on the grid. D. Abramson, M. Bernabeu, B. Bethwaite, K. Burrage, A. Corrias, C. Enticott, S. Garic, D. Gavaghan, T. Peachey, J. Pitt-Francis, E. Pueyo, B. Rodríguez, A. Sher, K. Tan. Philos Trans R Soc Lond A, vol. 368, pp. 3907–3923, 2010.

- Arrhythmic Risk Biomarkers for the Assessment of Drug Cardiotoxicity: from experiments to computer simulations. A. Corrias, X. Jie, L. Romero, M.J. Bishop, M.O. Bernabeu, E. Pueyo, B. Rodríguez. Philos Trans R Soc Lond A, vol. 368, pp. 3001–3025, 2010.

- Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk. E. Pueyo, Z. Husti, T. Hornyik, I. Baczkó, P. Laguna, A. Varró, B. Rodríguez. Am J Physiol, vol. 298, pp. 1577–1587, 2010.

- Dispersion of APD restitution quantified from the surface ECG. A. Mincholé, E. Pueyo, P. Laguna. Electrocardiol, vol. 43, pp. 643–644, 2010. Published in abstract form.

CONFERENCE PROCEEDINGS

- Analysis and improvement of a human ventricular cell model for investigation of cardiac arrhythmias. J. Carro, J.F. Rodríguez, P. Laguna, E. Pueyo. Proc. Computing in Cardiology, vol. 36, pp. 817–820, 2010.

- Torsadogenic drug-induced increased short-term variability of JTarea. X. Jie, B. Rodríguez, E. Pueyo. Proc. Computing in Cardiology, vol. 36, pp. 353–356, 2010.

- A vectorial approach for evaluation of depolarization changes during myocardial ischemia. D. Romero, M. Ringborn, P. Laguna, O. Pahlm, E. Pueyo. Proc. Computing in Cardiology, vol. 36, pp. 265–268, 2010.

- Potential pharmacological therapies for atrial fibrillation. A computational study. C. Sánchez, A. Corrias, P. Laguna, M. Davies, J. Swinton, I. Jacoboson, E. Pueyo, B. Rodríguez. Proc. Computing in Cardiology, vol. 36, pp. 413–416, 2010.

- Evaluation of a method for quantification of restitution dispersion from the surface ECG. A. Mincholé, E. Pueyo, J.F. Rodríguez, E. Zacur, M. Doblaré, P. Laguna. Proc. Computing in Cardiology, vol. 36, pp. 773–776, 2010.

- A new ECG biomarker for drug toxicity: a combined signal processing and computational modeling study. X. Jie, B. Rodríguez, E. Pueyo. Proc. 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS 10), pp. 2565–2568, 2010.

2009

JOURNAL PUBLICATIONS

- Impact of ionic current variability on human ventricular cellular electrophysiology. L. Romero, E. Pueyo, M. Fink, B. Rodríguez. Am J Physiol, vol. 297(4), pp. 1436–1445, 2009.

- Cardiac repolarisation analysis using the surface ECG. E. Pueyo, J.P. Martínez, P. Laguna. Philos Trans R Soc Lond A, vol. 367, pp. 313–323, 2009.

CONFERENCE PROCEEDINGS

- Transmural Differences in Rate Adaptation of Repolarization Duration Quantified from ECG Repolarization Interval Dynamics. A. Minchole, E. Pueyo, P. Laguna. Proc. Computers in Cardiology, vol. 35, pp. 597–600, 2009.

- Spatial Characterization of Ischemia in 12-lead ECG Recordings during PCI using both Depolarization and Repolarization Indices. D. Romero, E. Pueyo, M. Ringborn, P. Laguna. Proc. Computers in Cardiology, vol. 35, pp. 113–116, 2009.

- Cardiac Memory in Human Atria and Relation to Arrhythmogenesis. C. Sánchez, E. Pueyo, P. Laguna, B. Rodríguez. Proc. Computers in Cardiology, vol. 35, pp. 113–116, 2009.

2008

JOURNAL PUBLICATIONS

- QRS slopes for detection and characterization of myocardial ischemia. E. Pueyo, L. Sörnmo, P. Laguna. IEEE Trans Biomed Eng, vol. 55(2), pp. 468–477, 2008.

- A dynamic model to characterize beat-to-beat adaptation of repolarization to heart rate changes. E. Pueyo, M. Malik, P. Laguna. Biomed Signal Process Control, vol. 3, pp. 29–43, 2008.

2007

JOURNAL PUBLICATIONS

- Evaluation of QRS Slopes for Determination of Myocardial Damage in Chronic Chagasic Patients. E. Pueyo, E. Laciar, E. Anzuola, P. Laguna, R. Jané. Journal of Physics Conference Series, vol. 90, num. 012077, 2007.

CONFERENCE PROCEEDINGS

- Study of the Dynamic Relationship between T Wave Morphology Changes and Heart Rate during Ischemia. F. Simón, P. Laguna, E. Pueyo. Proc. Computers in Cardiology, vol. 34, pp. 297–300, 2007.

- Assessment of Myocardial Damage in Chronic Chagasic Patients using QRS Slopes. E. Pueyo, E. Laciar, E. Anzuola, P. Laguna, R. Jané. Proc. Computers in Cardiology, vol. 34, pp. 725–728, 2007.

- Dynamic Repolarization Assessment and Arrhythmic Risk Stratification. E. Pueyo, M. Malik, P. Laguna. Proc. 11th Mediterranean Conference on Medical and Biological Engineering and Computing, vol. 16, 2007.

2006

JOURNAL PUBLICATIONS

- QT variability and HRV interactions in ECG: quantification and reliability. R. Almeida, S. Gouveia, A.P. Rocha, E. Pueyo, J.P. Martínez, P. Laguna. IEEE Trans Biomed Eng, vol. 53(7), pp. 1317–1329, 2006.

2005

CONFERENCE PROCEEDINGS

- High-frequency signature of the QRS complex across ischemia quantified by QRS slopes. E. Pueyo, A. Arciniega, P. Laguna. Proc. Computers in Cardiology, vol. 32, pp. 659–662, 2005.

- Beat-to-beat adaptation of QT interval to heart rate. E. Pueyo, M. Malik, P. Laguna. Proc. 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS 05), pp. 769–772, 2005.

2004

JOURNAL PUBLICATIONS

- Time course of ECG depolarization and repolarization changes during ischemia in PTCA recordings. E. Pueyo, J. García, G.Wagner, R. Bailón, L. Sörnmo, P. Laguna. Methods Inf Med, vol. 43(1), pp. 43– 46, 2004.

- Individual patterns of dynamic QT/RR relationship in survivors of acute myocardial infarction and their relationship to antiarrhythmic efficacy of amiodarone. P. Smetana, E. Pueyo, K. Hnatkova, V. Batchvarov, P. Laguna, M. Malik. J Cardiovasc Electrophysiol, vol. 15(10), pp. 1147–1154, 2004.

- Characterization of QT interval adaptation to RR interval changes and its use as a risk-stratifier of arrhythmic mortality in amiodarone-treated survivors of acute myocardial infarction. E. Pueyo, P. Smetana, P. Caminal, A. Bayés de Luna, M. Malik, P. Laguna. IEEE Trans Biomed Eng, vol. 51(9), pp. 1511–1520, 2004.

- Assessment of the individual QT/RR relationship and hysteresis in post-infarction patients. E. Pueyo, P. Smetana, P. Laguna, M. Malik. Ital Heart J, vol. 5(1), pp. 165–168, 2004.

- Speed of QT rate adaptation predicts risk in myocardial infarction survivors. P. Smetana, E. Pueyo, H. Hnatkova, V. Batchvarov, M. Malik. J Am Coll Cardiol, vol. 43(5), pp. 108–109, 2004. Published in abstract form.

- Both beta-blockers and amiodarone increase speed of QT/heart rate adaptation. P. Smetana, E. Pueyo, H. Hnatkova, V. Batchvarov, M. Malik. J Am Coll Cardiol, vol. 43(5), pp. 494–494, 2004. Published in abstract form.

CONFERENCE PROCEEDINGS

- Quantification of the QT variability related to HRV: robustness study facing automatic delineation and noise on the ECG. R. Almeida, E. Pueyo, J. P. Martínez, A. P. Rocha, P. Laguna. Proc. Computers in Cardiology, vol. 31, pp. 769–772, 2004.

2003

JOURNAL PUBLICATIONS

- Effect of amiodarone on the descending limb of the T wave. P. Smetana, E. Pueyo, K. Hnatkova, V. Batchvarov, A. J. Camm, M. Malik. Am J Cardiol, vol. 92(6), pp. 742–746, 2003.

- Estimation of the QT/RR hysteresis lag. E. Pueyo, P. Smetana, P. Laguna, M. Malik. J Electrocardiol, vol. 36, pp. 187–190, 2003.

- Antiarrhythmic efficacy of amiodarone is predicted by changes in the QT/RR relationship. P. Smetana, E. Pueyo, H. Hnatkova, V. Batchvarov, A. J. Camm, M. Malik. Eur Heart J, vol. 24, pp. 720–720, 2003. Published in abstract form.

- Lack of QT prolongation with amiodarone increases arrhythmic risk. P. Smetana, E. Pueyo, H. Hnatkova, M. Malik. J Am Coll Cardiol, vol. 41(6), pp. 103–103, 2003. Published in abstract form.

- Amiodarone increases transmural heterogeneity of repolarization in patients with cardiac death. P. Smetana, E. Pueyo, H. Hnatkova, M. Malik. J Am Coll Cardiol, vol. 41(6), pp. 109–110, 2003. Published in abstract form.

CONFERENCE PROCEEDINGS

- A parametric model approach for quantification of short term QT variability uncorrelated with heart rate variability. R. Almeida, E. Pueyo, J. P. Martínez, A. P. Rocha, S. Olmos, P. Laguna. Proc. Computers in Cardiology, vol. 30, pp. 165–168, 2003.

- Evaluation of QT interval response to marked RR interval changes selected automatically in ambulatory recordings. E. Pueyo, P. Smetana, M. Malik, P. Laguna. Proc. Computers in Cardiology, vol. 30, pp. 157–160, 2003.

2002

JOURNAL PUBLICATIONS

- Modification of QT/RR adaptation by amiodarone is related to reduction in arrhythmic mortality in post-myocardial infarction patients. E. Pueyo, V. Batchvarov, P. Smetana, M. Malik. Circulation, vol. 106(19), pp. 373–374, 2002. Published in abstract form.

CONFERENCE PROCEEDINGS

- Time for QT adaptation to RR Changes and relation to arrhythmic mortality reduction in amiodarone-treated patients. E. Pueyo, P. Smetana, K. Hnatkova, P. Laguna, M. Malik. Proc. Computers in Cardiology, vol. 29, pp. 565–568, 2002.

- Time course of ECG depolarization and repolarization changes during ischemia in PTCA recordings. E. Pueyo, J. García, G.Wagner, R. Bailón, L. Sörnmo, P. Laguna. Proc. IV International Workshop on Biosignal Interpretation, pp. 115–118, 2002.