I received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, I was a research student at the Department of Mathematics, University of Zaragoza, where I developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 I started my Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. My Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, I also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and I was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where I worked under the supervision of Prof. Marek Malik.
After finishing my PhD in December 2006, I moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. I worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with an increased arrhythmic risk. Most of the studies conducted during my postdoctoral period involved the collaboration with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.
In January 2011 I was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 I worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, I work with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, my current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.
Since October 2015 I am back to my Associate Professor position at the University of Zaragoza. I have participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. I am currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, where we use a systems biology approach to investigate the aging of the human heart.